IGKC Mouse Monoclonal Antibody [Clone ID: KLC709]

Specifications

Product Data
Clone Name	KLC709
Applications	FC, IHC
Recommend Dilution	ELISA: Use Antibody without BSA for Coating. Flow Cytometry: 0.5-1 μg/106 cells. Immunohistochemistry on Frozen Sections: 0.5-1 μg/ml for 30 min at RT. Positive Control: 293T, Raji or hPBL cells, Tonsil or Spleen.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human Ig kappa chain.
Specificity	This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant. Cellular Localization: Cell Surface, cytoplasmic and secreted.
Formulation	10mM PBS State: Purified State: Liquid purified IgG fraction from Bioreactor Concentrate Stabilizer: 0.05% BSA Preservative: 0.05% Sodium Azide
Concentration	lot specific
Purification	Protein A/G Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C.
Predicted Protein Size	~22.5 kDa
Gene Name	immunoglobulin kappa constant
Database Link	Entrez Gene 3514 Human UniProt ID P01601
Synonyms	HCAK1, Ig Kappa Chain C Region, IGKC, Immunoglobulin KM
Reference Data

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