CD56 (NCAM1) Mouse Monoclonal Antibody [Clone ID: 123C3.D5 + 123A8]

CAT#: AM50240PU-S

CD56 (NCAM1) mouse monoclonal antibody, clone 123C3.D5 + 123A8, Purified

Size: 20 ug 100 ug



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CNY 5,830.00


货期*
5周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name 123C3.D5 + 123A8
Applications FC, IF, IHC, IP, WB
Recommend Dilution Flow Cytometry: 0.5-1 μg/million cells.
Immunofluorescence: 0.5-1 μg/ml.
Western Blotting: 0.5-1 μg/ml.
Immunoprecipitation: 1-2 μg/500 μg protein lysate.
Immunohistochemistry on Frozen and Formalin-Fixed Paraffin Sections: 0.5-1.0 μg/ml for 30 minutes at RT.
Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.
Positive Control: Cerebellum, Pancreas, Neuroblastoma.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Membrane preparation of a small cell lung carcinoma.
Specificity This Monoclonal Antibody reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene.
The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma).
Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.
Cellular Localization: Cell surface.
Formulation 10mM PBS
State: Purified
State: Liquid purified IgG fraction from Bioreactor Concentrate
Stabilizer: 0.05% BSA
Preservative: 0.05% Sodium Azide
Concentration lot specific
Purification Protein A/G Chromatography
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C.
Predicted Protein Size 180, 145 and 125 kDa
Gene Name neural cell adhesion molecule 1
Synonyms NCAM-1, N-CAM-1, NCAM
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Prion diseases
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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