PCBP1 Mouse Monoclonal Antibody [Clone ID: AT2A10]

Specifications

Product Data
Clone Name	AT2A10
Applications	ELISA, WB
Recommend Dilution	The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:500.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human PCBP1 (1-163aa) purified from E. coli
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-A affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	poly(rC) binding protein 1
Database Link	Entrez Gene 5093 Human UniProt ID Q15365
Background	PCBP-1 and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. PCBP1 constitutes a set of polypeptides that contribute to mRNA transcription, pre-mRNA processing as well as mature mRNA transport to the cytoplasm and translation. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA.
Synonyms	hnRNP E1, HNRPE1, HNRPX, Alpha-CP1, SUB2.3
Reference Data
Protein Pathways	Spliceosome

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