DIABLO Mouse Monoclonal Antibody [Clone ID: AT19F2]

CAT#: AM50051PU-S

DIABLO mouse monoclonal antibody, clone AT19F2, Purified

Size: 50 ul 100 ul



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CNY 5,630.00


货期*
5周

规格
    • 50 ul

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Specifications

Product Data
Clone Name AT19F2
Applications ELISA, WB
Recommend Dilution The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:3000.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Recombinant human SMAC/Diablo (56-239aa) purified from E. coli
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein-A affinity chromatography
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name diablo IAP-binding mitochondrial protein
Background SMAC/Diablo is one of the proapoptotic proteins. SMAC promotes caspase activation in the cytochrome c/Apaf-1/caspase-9 pathway by binding to inhibitor of apoptosis proteins (IAPs) and removing their inhibitory activity. In healthy cells, SMAC is a mitochondrial protein, but when cells undergo apoptosis, SMAC is released into the cytosol. SMAC is ubiquitously expressed with highest expression in testis. Expression is also high in heart, liver, kidney, spleen, prostate and ovary. Low in brain, lung, thymus and peripheral blood leukocytes
Synonyms 0610041G12Rik; DIABLO-S; FLJ10537; FLJ25049; SMAC; SMAC3
Reference Data
Protein Families Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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