AKR7A3 Mouse Monoclonal Antibody [Clone ID: AT2E11]

Specifications

Product Data
Clone Name	AT2E11
Applications	ELISA, WB
Recommend Dilution	ELISA. Western blot (1:1000).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human AKR7A3 (1-331aa) purified from E. coli
Specificity	The antibody recognizes human AKR7A3. Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
Database Link	Entrez Gene 22977 Human UniProt ID O95154
Background	Aldo-keto reductase family 7, member A 3 (AKR7A3) is a member of the aldo/keto reductase superfamily involved in the detoxification and metabolism of a variety of exogenous aldehydes and ketones. The activity of AKR7A3 may detoxify the aflatoxin B1 (AFB1) dialdehyde, which reacts with proteins, and thereby inhibitis AFB1 induced toxicity. AKR7A3 is expressed in kidney, colon, pancreas, endometrium and adenocarcinoma.
Synonyms	AFAR2
Reference Data
Protein Families	Druggable Genome

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