LAMP1 Mouse Monoclonal Antibody [Clone ID: 5H6]

Specifications

Product Data
Clone Name	5H6
Applications	IF, WB
Recommend Dilution	Western Blot: 1/5000. Immunofluorescence: 1/2000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant full length Human LAMP1 expressed in and purified from E. Coli.
Specificity	Specific for the ~100k LAMP1 protein.
Formulation	PBS State: Aff - Purified State: Liquid purified IgG fraction from Tissue Culture Supernatant Preservative: 10mM Sodium Azide
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	lysosomal associated membrane protein 1
Database Link	Entrez Gene 3916 Human UniProt ID P11279
Background	Lysosomal Associated Membrane Protein1 (LAMP1) is a protein that is localized primarily in lysosomes but may also be present on late endosomes and the plasma membrane. LAMP1 antibodies are therefore widely used as lysosome markers. It has recently been suggested that lysosomes are activated in microglia in the progression of multiple system atrophy (MSA) and thus play a key role in its pathology (Makioka et al., 2012).
Synonyms	LAMP-1, LAMPA, LGP120
Reference Data

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