RBFOX1 (N-term) Mouse Monoclonal Antibody [Clone ID: 1G10]

Specifications

Product Data
Clone Name	1G10
Applications	IF, WB
Recommend Dilution	Western Blot: 1/5000.  Immunofluorescence:  1/50-1/100.
Reactivity	Bovine, Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant protein taken from the N-terminus of human FOX1 expressed in and purified from E. Coli.
Specificity	Specific for the ~46/48k FOX1 protein doublet.
Formulation	PBS State: Aff - Purified State: Liquid purified IgG fraction from Tissue Culture Supernatant. Preservative: 10mM Sodium Azide
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	RNA binding protein, fox-1 homolog 1
Database Link	Entrez Gene 54715 Human UniProt ID Q9NWB1
Background	FOX1, also known as ataxin-2 binding protein 1 (A2BP1), is a neuron specific RNA-binding protein that has been shown to regulate a wide range of alternative splicing events implicated in neuronal development and maturation including transcription factors and synaptic proteins (Fogel et al., 2012). Defects in FOX1 have also been associated with autism (Martin et al., 2007), attention-deficit hyperactivity disorder (Elia et al., 2010) and schizophrenia (Xu et al., 2008).
Synonyms	HRNBP1, Ataxin-2-binding protein 1
Reference Data

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