Ficolin 2 (FCN2) Mouse Monoclonal Antibody [Clone ID: GN5]

Specifications

Product Data
Clone Name	GN5
Applications	ELISA, IP, WB
Recommend Dilution	Immuno Assays Immunoprecipitation. Western blot (Non-Reducing Conditions): Use 1/10 as a starting working dilution. Using non-reduced samples only weak signals are obtained.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	L-Ficolin/P35 isolated from Human plasma
Specificity	The monoclonal antibody GN5 recognizes L-Ficolin/P35.
Formulation	PBS State: Purified State: Liquid 0.2 µm filtered Ig fraction Stabilizer: 0.1% BSA
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	ficolin 2
Database Link	Entrez Gene 2220 Human UniProt ID Q15485
Background	Ficolins are a group of proteins containing both a collagen-like domain and a fibrinogen-like domain. They are found in various tissues. The domain organizations between ficolins and mannose binding lectin (MBL) are similar, although the carbohydrate-binding moieties are different. In man two types of ficolins (Lficolin/ P35 and H-ficolin) are present in serum and one type (M-ficolin) in cells. L-ficolin/P35 (also L-ficolin, ficolin L, EBP-37 or hucolin) is produced primarily by the liver. The association between L-ficolin/P35 and MASPs/sMAP is Ca2+-dependent. MASPs in L-ficolin/P35-MASP complexes have proteolytic activities for C4, C2 and C3. L-ficolin/P35 also shows opsonic activity.
Synonyms	FCN2, FCNL, Ficolin2, Ficolin-B, Ficolin-beta, L-ficolin, Serum lectin p35, 37 kDa elastin-binding protein, EBP-37, Hucolin
Reference Data

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