EMA (MUC1) Mouse Monoclonal Antibody [Clone ID: 214D4]
CAT#: AM32798PU-N
EMA (MUC1) mouse monoclonal antibody, clone 214D4, Purified
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CNY 5,290.00
货期*
5周
规格
Specifications
Product Data | |
Clone Name | 214D4 |
Applications | FC, IHC |
Recommend Dilution | Flow Cytometry. Immunohistochemistry on Frozen Sections. Immunohistochemistry on Paraffin Sections (10 µg/ml). |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Derived by fusion of SP2/0 mouse myeloma cells with spleen cells from a BALB/c Mouse immunized with a fusion protein, Human beta-Gal-Episialin/MUC1 repeat domain. |
Specificity | This Monoclonal 214D4 antibody is directed against the repeat domain of Episialin. |
Formulation | PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide |
Concentration | lot specific |
Conjugation | Unconjugated |
Gene Name | mucin 1, cell surface associated |
Database Link | |
Background | Mucin 1, cell surface associated (MUC-1) or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene in humans. MUC-1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with colon, breast, ovarian, lung and pancreatic cancers. |
Synonyms | MUC-1, PEMT, Episialin, EMA, H23AG, PUM, DF3, CA 15-3 |
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