TRK fused gene (TFG) Mouse Monoclonal Antibody [Clone ID: TFG-03]

Specifications

Product Data
Clone Name	TFG-03
Applications	IF, IHC, IP, WB
Recommend Dilution	Immunoprecipitation. Western Blotting. Immunocytochemistry. Immunohistochemistry on Paraffin Sections: 5 µg/ml.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein Trx-his-NTFG.
Specificity	This Monoclonal antibody TFG-03 recognizes TFG, an approximately 50 kDa protein with regulatory functions.
Formulation	PBS, pH 7.4 State: Purified State: Liquid purified IgG fraction (> 95% by SDS-PAGE) Preservative: 15 mM Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	TRK-fused gene
Database Link	Entrez Gene 10342 Human UniProt ID Q92734
Background	TFG (TRK-fused gene protein) is a regulatory protein with not fully understood function. Its defects are associated with various carcinomas, such as e.g. melanoma, thyroid papillary carcinoma, or glioma. TFG structure (multiple protein interaction motifs) indicated it can be an adaptor protein. It has been demonstrated TFG interacts with proteins modulating the NFkappaB pathway (TANK and NEMO). TNG enhances the effect of TNFalpha, TANK, TRAF2 and TRAF6 in inducing NFkappaB activity.
Synonyms	TRK-fused gene protein
Reference Data

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