CD11a (ITGAL) Mouse Monoclonal Antibody [Clone ID: 87-6F9]
CAT#: AM32398PU-N
CD11a (ITGAL) mouse monoclonal antibody, clone 87-6F9, Purified
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CNY 4,724.00
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Specifications
Product Data | |
Clone Name | 87-6F9 |
Applications | IHC |
Recommend Dilution | Flow Cytometry. Immunohistochemistry on frozen section. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | A BALB/c mouse was immunized and SP2/0 cells were used for fusion with splenocytes. |
Specificity | This antibody reacts to CD11a. |
Formulation | PBS State: Purified State: Liquid purified Ig fraction Preservative: 0.05% sodium azide |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C. |
Gene Name | integrin subunit alpha L |
Database Link | |
Background | CD11a is expressed on lymphocytes, granulocytes, monocytes and macrophages with increase in levels on memory T cells. CD11a or LFA-1 has a key role in mediating leukocyte adhesion to endothelium during inflammatory responses through binding to ICAM-1 (CD54). Other ligands are ICAM-2 and ICAM-3. It is also involved in many T cell functions and immune phenomena. Mol. weight in SDS gels is about 180 kD. Part of heterodimer with CD18 (integrin beta-2). A defect in beta-2 expression results in leucocytes adhesion deficiency (LAD) in which patients suffer from recurring bacterial infections. |
Synonyms | Integrin alpha-L, LFA1, LFA-1 |
Reference Data |
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