RRP4 (EXOSC2) Mouse Monoclonal Antibody [Clone ID: 15B3]

Specifications

Product Data
Clone Name	15B3
Applications	ELISA
Recommend Dilution	ELISA.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant GST-hRRP4 (NCBI accession number NM_014285 REGION 3-884, expression vector pGEX-4T3), expressed in E.coli.
Specificity	Specificity has been tested in ELISA. Additional tests for cross reactivity have not yet been performed.
Formulation	10 mM Ammonium Bicarbonate buffer State: Purified State: Lyophilized purified Ig fraction Stabilizer: 2 mg BSA
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	exosome component 2
Database Link	Entrez Gene 23404 Human UniProt ID Q13868
Background	The exosome, present in both the nucleus and cytoplasm of all eukaryotic cells, is a complex of 3'-5' exoribonucleases containing at least nine core components. Recently, it has been demonstrated, mainly by analyses in yeast, that the nuclear exosome is essential for rRNA processing and sn(o)RNA biogenesis. Furthermore, it is involved in the degradation of improperly processed mRNAs. The cytoplasmic exosome participates in normal mRNA turnover and in the degradation of inherently instable mRNAs that contain AU-rich elements. Therefore, the exosome plays a key role in RNA metabolism.
Synonyms	Exosome component 2
Reference Data

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