C5R1 (C5AR1) Rat Monoclonal Antibody [Clone ID: 8D6]

CAT#: AM31865BT-N

C5R1 (C5AR1) rat monoclonal antibody, clone 8D6, Biotin

Conjugation: Unconjugated Biotin FITC PE



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CNY 4,554.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Clone Name 8D6
Applications FC
Recommend Dilution Flow Cytometry.
Immunohistochemistry on frozen sections.
Rezeptor blockage assays (unpublished results).

Tissue Distribution by Flow Cytometry Analysis:
Cell Source: Human PBL
Cell Concentration: 1x10e6 cells per test
Antibody Concentration Used: 1.0 μg/10e6 cells
Secondary Antibody: Streptavidin FITC 1/500 dilution
Reactivity Human
Host Rat
Clonality Monoclonal
Immunogen RBL-2H3 (rat basophilic leukemia) transfected cells expressing human C5aR on the cell surface
Donor: Lou/c rat spleen cells
Specificity This monoclonal antibody detects an epitope on the N terminus (aa 1-15) of the human C5a receptor (also known as CD88) found on human myeloid cells including granulocytes and monocytes/macrophages. It does not bind to tubular epithelial cells in situ under normal or inflammatory conditions. C5aR binds to C5a, a 74 aa peptide cleaved from complement protein C5. C5a receptor has seven transmembrane segments and is a member of the rhodopsin subfamily of G protein coupled receptors.
Formulation PBS containing 0.02% sodium azide (NaN3) as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.
Label: Biotin
State: Liquid purified Ig fraction
Concentration lot specific
Purification Affinity chromatography on Protein G
Conjugation Biotin
Storage Condition Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Gene Name complement component 5a receptor 1
Synonyms C5a-R, C5aR, C5AR1, Complement Component 5a Receptor 1
Reference Data
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Complement and coagulation cascades, Neuroactive ligand-receptor interaction
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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