CD68 Mouse Monoclonal Antibody [Clone ID: Y1/82A]

Specifications

Product Data
Clone Name	Y1/82A
Applications	FC, IHC
Recommend Dilution	Flow Cytometry: intracellular staining. Immunohistochemistry on Frozen Sections.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Lysosomal contents of lung macrophages
Specificity	This antobody recognizes CD68 (LAMP4), a 110 kDa glycoprotein expressed mainly in cytoplasmic granules of monocytes/macrophages, granulocytes, and dendritic cells.
Formulation	Phosphate buffered saline (PBS), pH~7.4 State: Purified State: Liquid purified Ig fraction Preservative: 15 mM Sodium Azide
Concentration	lot specific
Purification	Protein-A Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	CD68 molecule
Database Link	Entrez Gene 968 Human UniProt ID P34810
Background	CD68 (also known as LAMP4 or SCARD1) is a 110 kDa type I transmembrane glycoprotein of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and the scavenger receptor family. Although CD68 primarily localizes to lysosomes and endosomes, its fraction circulates to the cell surface. By the heavily glycosylated extracellular domain CD68 binds to tissue- and organ-specific lectins or selectins. It is expressed mainly in cytoplasmic granules of monocytes/macrophages, granulocytes, and dendritic cells, but also e.g. in a proportion of epithelial tumours (diagnosis of poorly differentiated neoplasms).
Synonyms	Gp110, Macrosialin, Macrophage marker
Reference Data

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