TNFSF12-TNFSF13 Mouse Monoclonal Antibody [Clone ID: CARL-1]

CAT#: AM26783PU-N

TNFSF12-TNFSF13 mouse monoclonal antibody, clone CARL-1, Purified

Conjugation: Unconjugated PE



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CNY 3,140.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Clone Name CARL-1
Applications FC, FN
Recommend Dilution Flow cytometry.
Functional application: Neutralization.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Human CD255-transfected 2PK-3 cells
Specificity This antobody recognizes CD255 / TWEAK, a type II transmembrane protein of the TNF superfamily able to weakly induce apoptosis in many cell types.
Formulation Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide.
State: Purified
State: Liquid Ig fraction
Preservative: 15 mM sodium azide, approx. pH 7.4
Concentration lot specific
Purification Protein-A affinity chromatography
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C.
DO NOT FREEZE!
Gene Name TNFSF12-TNFSF13 readthrough
Background CD255 / TWEAK (TNF-related weak inducer of apoptosis), a type II transmembrane protein expressed as membrane-bound and secreted form, can induce apoptosis in many tissues and cell lines through its receptor CD266 / TWEAK R. On the other hand, in endothelial cells this interaction can induce proliferation and promote angiogenesis including neovascularization of tumours. CD255 can act in a juxtacrine manner to initiate cellular responses, and induces secretion of pro-inflammatory cytokines. Besides CD266, CD255 may also bind to DR3.
Synonyms APO3 ligand, APO3L, DR3LG
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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