C5L2 (C5AR2) Mouse Monoclonal Antibody [Clone ID: 1A6]

Specifications

Product Data
Clone Name	1A6
Applications	IHC
Recommend Dilution	Immunohistochemistry on paraffin sections: 2 µg/ml (1/200); pretreatment with microwave required. Positive control: human hippocampus.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	DNA vaccine
Specificity	This antibody detects Human GPR77.
Formulation	Phosphate buffered saline pH 7.2 (PBS) State: Purified State: Lyophilized affinity purified Ig fraction Stabilizer: 5mg/ml bovine serum albumin (BSA) Preservative: 0.1% Kathon
Reconstitution Method	Restore by adding 0.5 ml distilled water
Concentration	0.4 mg/ml IgG (after reconstitution)
Purification	Protein G Chromatography
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	complement component 5a receptor 2
Database Link	Entrez Gene 27202 Human UniProt ID Q9P296
Background	GPR77 or C5L2 is a 337 amino acid protein that belongs to the G - protein coupled receptor 1 family, with a potential glycosylation site and one disulfide bond. Phagocytes and kidney tissue have shown differential regulation of C5L2 and the other C5a receptor, CD88. The two receptors for C5a appear to have distinct functional roles.
Synonyms	G-protein coupled receptor 77
Reference Data

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