CCR1 (305-319) Mouse Monoclonal Antibody [Clone ID: 293]

Specifications

Product Data
Clone Name	293
Applications	ELISA
Recommend Dilution	ELISA: Reacts with the CCR1 peptide KLH conjugate (Immunogen) in indirect ELISA assay.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	A 15 amino - acid peptide corresponding to the amino acid sequence 305-319 on human CCR1 conjugated with KLH
Specificity	This antibody is reactive to CCR1 conjugated KLH. The antibody does not cross react with KLH, BSA and HSA.
Formulation	0.01M PBS, pH 7.0 State: Purified State: Lyophilized ig fraction
Reconstitution Method	Restore with double distilled water to adjust the final concentration to 1.0 mg/ml.
Concentration	lot specific
Purification	Protein G affinity purified
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	C-C motif chemokine receptor 1
Database Link	Entrez Gene 1230 Human UniProt ID P32246
Background	CCR1, also called CD191, is the first CC chemokine receptor identified at DNA level. Like other CC chemokine receptors, CCR1 is a G-protein coupled 7 transmembrane protein. Genes for CCR1 and several other chemokine forms a cluster on chromosome 3p. A number of CC chemokines, such as MIP-1β, Rentes, MIP1- α , MIP1- δ , RANTES, and MIP3, MIP1 γ, HCC1 and HCC4 have been found to be the ligands of CCR1. CCR1 expression has been reported to be implicated in rheumatoid arthritis, chronic lymphocytic leukemia and hairy cell leukemia.
Synonyms	C-C chemokine receptor type 1, C-C CKR-1, CC-CKR-1, CCR-1, CMKBR1, CMKR1, SCYAR1, HM145, LD78 receptor
Reference Data

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