TUBGCP2 (2-194) Mouse Monoclonal Antibody [Clone ID: GCP2-01]

Specifications

Product Data
Clone Name	GCP2-01
Applications	IF, IHC, IP, WB
Recommend Dilution	Immunoprecipitation. Western blot (reducing conditions): 1-2 µg/ml. Immunocytochemistry. Immunohistochemistry on paraffin sections.
Reactivity	Human, Mouse, Porcine, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	GST-fusion protein containing amino acids 2-194 of mouse GCP2
Specificity	The antibody recognizes gamma-tubulin complex component 2 (GCP2), a 95-103 kDa protein. It recognizes also phosphorylated GCP2.
Formulation	Phosphate buffered saline (PBS), approx. pH 7.4 State: Aff - Purified State: Liquid Ig fraction Preservative: 15 mM sodium azide
Concentration	lot specific
Purification	Protein-A affinity chromatography (> 95% by SDS-PAGE)
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	tubulin gamma complex associated protein 2
Database Link	Entrez Gene 10844 Human UniProt ID Q9BSJ2
Background	Gamma tubulin complex component 2 (GCP2) is 95-103 kDa protein which associates with two molecules of gamma tubulin and one molecule of gamma tubulin complex component 3 (GCP3), to form the gamma tubulin small complexes (gammaTuSCs). These complexes interact with GCP4, 5, and 6 to form the gamma tubulin ring complexes (gammaTuRCs), which are embedded in the microtubule organizing center matrix where they nucleate microtubules. The gammaTuRCs are also involved in the regulation of microtubule plus and minus end dynamics. Components of gamma tubulin complexes are highly conservative in eukaryotes.
Synonyms	GCP-2, GCP2, Spc97, Grip103
Reference Data

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