C3 Mouse Monoclonal Antibody [Clone ID: 2B10B9B2]

Specifications

Product Data
Clone Name	2B10B9B2
Applications	ELISA, WB
Recommend Dilution	Immunoassays. Western blot: The typical starting working dilution is 1:50. Not useful for immunoprecipitation.
Reactivity	Rat
Host	Mouse
Clonality	Monoclonal
Specificity	The monoclonal antibody 2B10B9B2 reacts with an epitope on C3b. The antibody reacts both with intact C3 and C3b.
Formulation	State: Low Endotoxin Preservative: 0.02% sodium azide
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C.
Gene Name	complement component 3
Database Link	Entrez Gene 24232 Rat UniProt ID P01026
Background	The complement factor C3 consists of an alpha- and a beta-chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical and mannose binding lectin activation pathways lead to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to formation of the alpha-chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues including renal epithelial cells and hepatocytes.
Synonyms	CPAMD1, Complement component 3
Reference Data

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