Ifng Rat Monoclonal Antibody [Clone ID: F1]

Specifications

Product Data
Clone Name	F1
Applications	ELISA, FN, IP
Recommend Dilution	Functional assays (purification or immunochemical investigation of mouse gamma Interferon and structural studies). Immunoassays (tracer antibody). Immunoprecipitation.
Reactivity	Mouse
Host	Rat
Clonality	Monoclonal
Specificity	Monoclonal antibody F1 binds both natural and recombinant mouse gamma Interferon. Its binding activity has been demonstrated in vitro and in vivo. F1 antibodies have been demonstrated to be able to inhibit inflammatory responses to bacterial lipopolysaccharides. These antibodies were furthermore shown to inhibit Shwartzman reactions and to protect NZB mice against spontaneous development of autoimmune disease. The neutralizing activity of the antibody has been demonstrated as being poor in anti-viral assays. If a neutralizing antibody is specifically desired, we recommend the use of another antibody, clone F3, which recognizes a different epitope on the murine gamma Interferon molecule and in contrast to F1, exhibits strong neutralizing activity.
Formulation	PBS State: Purified State: Liquid 0.2 µm filtered Ig fraction Stabilizer: 0.1% bovine serum albumin Preservative: 0.02% sodium azide
Concentration	lot specific
Purification	Protein G
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C.
Gene Name	interferon gamma
Database Link	Entrez Gene 15978 Mouse UniProt ID P01580
Synonyms	IFN-gamma, gamma IFN
Reference Data

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