Nectin2 (extracell. dom.) Rat Monoclonal Antibody [Clone ID: 502-57]
CAT#: AM26324FC-N
Nectin2 (extracell. dom.) rat monoclonal antibody, clone 502-57, FITC
Conjugation: Unconjugated
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CNY 8,738.00
货期*
5周
规格
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Specifications
Product Data | |
Clone Name | 502-57 |
Applications | ELISA, IHC, IP, WB |
Recommend Dilution | Immunohistochemitry on frozen sections. Flow cytometry: The typical starting working dilution is 1:10. Fixation with PFA or acetone/methanol is recommended. Immunoassays. Immunoprecipitation: The typical starting working dilution is 1:10. Fixation with PFA or acetone/methanol is recommended. Western blot: The typical starting working dilution is 1:10. Fixation with PFA or acetone/methanol is recommended. |
Reactivity | Human, Mouse |
Host | Rat |
Clonality | Monoclonal |
Immunogen | Extracellular domain of mouse nectin-2 |
Specificity | This antibody detects Nectin-2 at extracellular domain. |
Formulation | PBS Label: FITC State: Liquid Ig fraction Stabilizer: 0.1% bovine serum albumin Preservative: 0.02% sodium azide |
Concentration | lot specific |
Purification | Protein G |
Conjugation | FITC |
Storage Condition | Store at 2 - 8 °C. |
Gene Name | nectin cell adhesion molecule 2 |
Database Link | |
Background | Nectin (originally isolated as poliovirus receptor-related protein (PRR)) is a cell-cell adhesion molecule of the immunoglobulin supergene family. Nectin is colocalized with afadin at cadherin-based cell-cell adherence junctions in various tissues and cell lines. The nectin family consist of nectin-1, nectin-2 and nectin-3. Nectin-2 also known as PRR2 or CD112 is a plasma membrane adhesion molecule localized at adherens junctions which is widely expressed in various cell lines including neuronal, endothelial, epithelial and hematopoietic cells. Next to its role in adherens junctions it functions as alphaherpus virus receptor and acts also as intercellular adhesion molecule and pseudorabies virus receptor. Disruption of mouse nectin-2 leads to infertility of male mice. |
Synonyms | Nectin-2, PVRL2, HVEB, PRR2, Nectin-2 |
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