liver FABP (FABP1) Mouse Monoclonal Antibody [Clone ID: L2B10]

Specifications

Product Data
Clone Name	L2B10
Applications	ELISA, IHC, WB
Recommend Dilution	Immunoassay. Western blot. Immunohistochemistry on Fozen Sections. Immunohistochemistry on Paraffin Sections. Recommended Dilutions: Use 1/50 as a starting working dilution for immunohistochemistry and Western blotting.
Reactivity	Baboon, Canine, Human, Porcine, Rat
Host	Mouse
Clonality	Monoclonal
Specificity	The monoclonal antibody L2B10 recognizes Human Liver Fatty Acid Binding Protein (L-FABP) of both natural and recombinant origin. The monoclonal antibody L2B10 is useful to detect ischemic areas of Human liver. Furthermore, the antibody can be used for the purification of Human L-FABP. Weak reactivity with Human H-FABP.
Formulation	PBS State: Purified State: Liquid 0.2 µm filtered Ig fraction Stabilizer: 0.1% BSA Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Protein G Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	fatty acid binding protein 1
Database Link	Entrez Gene 2168 Human UniProt ID P07148
Background	The L-FABP protein is derived from the human FABP1 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. L-FABP is localized in the liver, kidney and intestinal epithelium.
Synonyms	FABPL, L-FABP, Liver-type fatty acid-binding protein
Reference Data

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