Complement C5 (C5) Mouse Monoclonal Antibody [Clone ID: 568]

Specifications

Product Data
Clone Name	568
Applications	ELISA, WB
Recommend Dilution	Immunoassays. Western blot: The typical starting working dilution is 1/10.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	Monoclonal antibody 568 reacts with an epitope on C5 and on C5b.
Formulation	PBS State: Purified State: Liquid 0.2 µm filtered Ig fraction Stabilizer: 0.1% BSA Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Protein G Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	complement component 5
Database Link	Entrez Gene 727 Human UniProt ID P01031
Background	C5 is involved in the activation of the lythic pathway within the complement system which is an important factor in innate immunity. The complement pathways can be divided in the activation pathways and lytic pathway. The activation pathways lead via C3 to the cleavage of the fifth complement component C5 into C5a and C5b. C5b initiates the assembly of the membrane attack complex (MAC) that mediates cytolysis.
Synonyms	CPAMD4, Complement component 5
Reference Data

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