Afdn (1814-1829) Mouse Monoclonal Antibody [Clone ID: 3]
CAT#: AM26175PU-N
Afdn (1814-1829) mouse monoclonal antibody, clone 3, Purified
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CNY 7,170.00
货期*
5周
规格
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Specifications
Product Data | |
Clone Name | 3 |
Applications | ELISA, IP, WB |
Recommend Dilution | Immunohistochemistry on frozen sections. Immunoassay. Immunoprecipitation. Western blot: The typical starting working dilution is 1:50. Fixation with PFA or acetone/methanol is recommended. |
Reactivity | Canine, Human, Mouse, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Peptide 1814-1829 aa of rat l-afadin |
Specificity | This antibody detects L-Afadin. |
Formulation | PBS State: Purified State: Liquid 0.2 µm filtered Ig fraction Stabilizer: 0.1% bovine serum albumin Preservative: 0.02% sodium azide |
Concentration | lot specific |
Purification | Protein G |
Conjugation | Unconjugated |
Storage Condition | Store at 2 - 8 °C. |
Gene Name | myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4 |
Database Link | |
Background | Afadin is an actin filament-binding protein that is involved in cell-cell adherens junctions (AJs) which directly interacts with the alpha herpus virus receptor, a member of the immunoglobulin supergene family. Afadin is colocalized with nectin at cadherin-based cell-cell adherence junctions in various tissues and cell lines. L-Afadin has been isolated as an F-actin-binding protein from rat brain. L-afadin is ubiquitously expressed and specifically localized at zonula adherens (ZA) in epithelial cells and at cell-cell adherens junctions (AJs) in non-epithelial cells. L-afadin has a splice variant, named small intestine absorptive afadin (s-afadin) which is abundantly expressed in neural tissue. |
Synonyms | Protein AF-6 |
Reference Data |
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