HLA II Mouse Monoclonal Antibody [Clone ID: HKB1]

Specifications

Product Data
Clone Name	HKB1
Applications	FC, IHC
Recommend Dilution	Immunohistochemistry on Frozen Sections: 1 µg/ml (1/400). Has been described to work in FACS.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	REH cells, a Human B cell precursor leukemia cell line.
Specificity	This antibody recognizes all HLA class II antigens, the 3 major (HLA-DP, -DQ and -DR) and 2 minor Major Histocompatibility Complex MHC class II proteins (HLA-DM and -DO).
Formulation	Stock solution contains PBS, pH 7.2 with 5 mg/ml BSA as a stabilizer and 0.09% Sodium Azide as preservative. State: Aff - Purified State: Lyophilized purified Ig fraction
Reconstitution Method	Restore by adding 0.5ml distilled water.
Concentration	0.4 mg/ml
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at 2-8°C. Following reconstitution store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Background	The genes of the class II combine to form heterodimeric (αβ) protein receptors that are typically expressed on the surface of antigen presenting cells (APCs): dendritic cells B-cells and macrophages. HLA class II is presented on acticvated T-cells. HLA class II molecules present exogenously derived antigen to the T cell receptor (TCR) on CD4+ T lymphocytes.
Synonyms	HLA ll, human leukocyte antigen class ll
Reference Data

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