Laminin alpha 4 (LAMA4) Mouse Monoclonal Antibody [Clone ID: 6C3]

Specifications

Product Data
Clone Name	6C3
Applications	ELISA, IP, WB
Recommend Dilution	ELISA: 1:4000. Western blot (reduced conditions): 1:1 000 – 1:2 000. Immunoprecipitation: 1:20.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Immunoaffinity-purified Laminin 411 (laminin-8 (alpha4beta1gamma1) from Platelets
Specificity	This antibody detects Laminin alpha 4.
Formulation	PBS pH 7.4, with 0.09% sodium azide State: Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Ion-exchange chromatography
Conjugation	Unconjugated
Storage Condition	Upon receipt, store (in aliquots) at -20 to -70 °C. Avoid repeated freezing and thawing.
Gene Name	laminin subunit alpha 4
Database Link	Entrez Gene 3910 Human UniProt ID Q16363
Background	Laminins are a family of large heterotrimeric proteins that promote cell adhesion and migration via integrins and other cell-surface receptors. They are major components of basement membranes of blood vessels and other tissue compartments, and are synthesized by numerous cell types. Through combination, laminin chains constitute 15 laminin isoforms. Laminin isoforms, particularly their alpha chain, are expressed in a celland tissue-specific manner, and are differentially recognized by integrins.
Synonyms	LAMA4, Laminin subunit alpha-4
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer

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