SIV Protein Nef Nef (71-80) Mouse Monoclonal Antibody [Clone ID: 17 (04-001)]

Specifications

Product Data
Clone Name	17 (04-001)
Applications	ELISA, IF, IHC, IP, WB
Recommend Dilution	Reacts in ELISA, Western blot, Immunoprecipitation, and Immunohistochemistry on frozen sections with Nef of SIVmac251 strain. (Piguet 1998, Khan 1998, Guillemin 2000). Reacts in Immunoflourescence with Nef of SIVmac239 strain and SIVmac1A11 strain. (Khan 1998, Chan 2005). ELISA: 1:10 000. Western blot: 1:1000.
Reactivity	Monkey
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant SIV-1 Mac251 Nef protein (purified from E. coli).
Specificity	This antibody detects SIV-1 Nef, mapped to aa 71-80 (Mapped to amino acids 71-80 (-PAAEREKLAY-). Reacts in ELISA, WB, RIP, IHC with Nef of SIVmac251 strain. (Piguet 1998, Khan 1998, Guillemin 2000). Reacts in IF with Nef of SIVmac239 strain and SIVmac1A11 strain. (Khan 1998, Chan 2005).
Formulation	PBS, pH 7.4, with 0.09% sodium azide State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Upon receipt, store (in aliquots) at -20 to -70 °C. Avoid repeated freezing and thawing.
Database Link	UniProt ID P12482
Background	The simian immunodeficiency virus (SIV) nef protein (Snef) is expressed at high levels early and throughout infection. This protein is a determinant of pathogenesis and disease progression in adult macaques infected with SIV.
Synonyms	Simian immunodeficiency virus Negative factor, F-protein
Reference Data

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