HIV-1 Nef Protein Mouse Monoclonal Antibody [Clone ID: JR6 (01-009)]

Specifications

Product Data
Clone Name	JR6 (01-009)
Applications	ELISA, IHC, IP, WB
Recommend Dilution	Reacts in ELISA and Western blot with HIV-1 Nef JR-CSF, BRU, IIIB, LAV, BH10 strains. Titer using rNef protein with subtype A aa. consensus: ELISA: 1: 25000. Western blot: 1: 5000.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody HIV-1 Nef regulatory protein. Mapped to amino acids 195-205 (ARELHPEYYKD – B subtype consensus). It recognizes the rNef of HIV-1 subtypes A, B and C.
Formulation	PBS pH 7.4, with 0.09% sodium azide State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Upon receipt, store (in aliquots) at -20 to -70 °C. Avoid repeated freezing and thawing.
Background	HIV is a highly variable virus which mutates very readily. This means there are many different strains of HIV, even within the body of a single infected person. The strains of HIV1 can be classified into three groups: the "major" group M, the "outlier" group O and the "new" group N. These three groups may represent three separate introductions of simian immunodeficiency virus into humans. Group O appears to be restricted to West-Central Africa and group N, discovered in 1998 in Cameroon, is extremely rare. More than 90% of HIV1 infections belong to HIV1 group M.
Synonyms	HIV1, HIV-I, Human immunodeficiency virus type 1
Reference Data

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