Amyloid beta (1-40 specific) Mouse Monoclonal Antibody [Clone ID: CV9 7B10]

Specifications

Product Data
Clone Name	CV9 7B10
Applications	ELISA
Recommend Dilution	ELISA: In combination with capturer anti-amyloid peptide N-terminal antibody (Clone NT 4A2, Cat.-No AM26042PU-N), the antibody can detect Aβ40 in Sandwich ELISA assay.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	C-terminal amino acid sequence of Human beta amyloid peptide 40, conjugated with KLH
Specificity	This antibody recognizes the C-terminal peptide of beta amyloid peptide 40, and full length beta amyloid peptide 40.
Formulation	0.01M PBS pH7.2 State: Aff - Purified State: Lyophilized purified IgG fraction
Reconstitution Method	Restore with Double distillated water is recommended to adjust the final concentration to 1.0 mg/ml.
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Upon receipt, store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Background	Aβ40, Aβ42 and Aβ43 are different only at the few C-end amino acids. While the C-end amino acids showed no speciesspecificity in mammalians, the Nterminal amino acid sequences have minor discrepancies between difference species. Amyloid beta peptides Aβ42 and Aβ40 have been investigated extensively for predicating Alzheimer’s disease. A recent study on A Aβ43 in brain showed that Aβ43 is more fibrillogenic than the other amyloid beta peptides and may be useful as a biomarker or therapeutic target for Alzheimer’s disease. Antibody to N-terminal sequence can bind to all the three amyloid beta peptides.
Reference Data

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