P Glycoprotein (ABCB1) Mouse Monoclonal Antibody [Clone ID: PG-13]

Specifications

Product Data
Clone Name	PG-13
Applications	IF, IHC, WB
Recommend Dilution	Western Blot: 0.5 - 1 μg/ml. Immunohistochemistry on paraffin and frozen sections: 1 - 2 μg/ml. Immunocytochemistry.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	A mixture of human and hamster drug-resistant whole cells and crude plasma membranes.
Specificity	This antibody reacts to CD243 / MDR1.
Formulation	1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative. State: Purified State: Lyphilized purified Ig fraction
Reconstitution Method	Restore with 1.2% sodium acetate or neutral PBS
Concentration	0,1 mg/ml (after reconstitution with PBS)
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	ATP binding cassette subfamily B member 1
Database Link	Entrez Gene 5243 Human UniProt ID P08183
Background	P-Glycoprotein,, also known as Multidrug Resistance 1 (MDR1), is one of the ATP-binding cassette transporters family. P-glycoprotein-1 is involved in the transport of 3 of these protease inhibitors in vitro.MDR1 gene is mapped to the 7q21.1 by in situ hybridization. The MDR1 gene product, P-glycoprotein,mediates the transport of the cardiac glycoside, digoxin.
Synonyms	Multidrug resistance protein 1, P-glycoprotein 1, ABCB1, PGY1
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways	ABC transporters

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