Caldesmon (CALD1) (smooth) Mouse Monoclonal Antibody [Clone ID: CD-7]

Specifications

Product Data
Clone Name	CD-7
Applications	IHC, WB
Recommend Dilution	Western Blot: 1 - 2 μg/ml. Immunohistochemistry on frozen and paraffin sections: 2 - 4 μg/ml.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Caldesmon from turkey gizzard
Specificity	This antibody reacts to Caldesmon (smooth).
Formulation	1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative. State: Aff - Purified State: Lyphilized purified Ig fraction
Reconstitution Method	Restore with 1.2% sodium acetate or neutral PBS
Concentration	0,1 mg/ml (after reconstitution with PBS)
Purification	Affinity chromatography
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	caldesmon 1
Database Link	Entrez Gene 800 Human UniProt ID Q05682
Background	Caldesmon is a potential actomyosin regulatory protein found in smooth muscle and nonmuscle cells.The predicted smooth-muscle polypeptide is 793 amino acids long. The high molecular weight caldesmon (h-CaD) is predominantly expressed in smooth muscles, whereas the low molecular weight caldesmon (l-CaD) is widely distributed in nonmuscle tissues and cells. Hayashi et al. (1992) demonstrated that the human CDM gene is composed of 14 exons.
Synonyms	CALD1, CAD, CDM
Reference Data
Protein Pathways	Vascular smooth muscle contraction

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