C Reactive Protein (CRP) Mouse Monoclonal Antibody [Clone ID: C2]

Specifications

Product Data
Clone Name	C2
Applications	ELISA
Recommend Dilution	ELISA: The antibody C2 has been tested as the Capture antibody in a Sandwich ELISA for analysis of Human C-Reactive Protein in combination with the antibody C6 (AM20204PU-N).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified human CRP
Specificity	The antibody C2 recognizes Human CRP, an 117 kDa plasma acute phase protein. It recognizes the antigen both in the presence and in the absence (samples containing EDTA) of Ca2+.
Formulation	Phosphate buffered saline (PBS), pH~7.4 with 15 mM Sodium Azide as preservative. State: Aff - Purified State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
Concentration	lot specific
Purification	Affinity Chromatography on Protein-A.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	C-reactive protein, pentraxin-related
Database Link	Entrez Gene 1401 Human UniProt ID P02741
Background	The C-reactive protein (CRP) is a cyclic pentameric pentraxin family acute phase protein compound of five identical noncovalently bound nonglycosylated subunits (each subunit 24 kDa; physiologic CRP molecule 117,5 kDa). CRP is produced by the liver and its plasma levels rise dramatically during inflammatory processes occuring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.) and is also believed to play an important role in innate immunity. Patients with elevated basal levels of CRP are at increased risk for hypertension and cardiovascular disease.
Synonyms	PTX1, C Reactive Protein, Pentraxin-related
Reference Data
Protein Families	Secreted Protein

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