GM CSF Receptor alpha (CSF2RA) Mouse Monoclonal Antibody [Clone ID: 4H1]

Specifications

Product Data
Clone Name	4H1
Applications	FC, IHC, IP, WB
Recommend Dilution	Flow Cytometry. Immunoprecipitation. Western blot. Immunohistochemistry on Frozen Sections.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	CD116-transfected COS cells
Specificity	This antibody recognizes Human CD116, the GM-CSF receptor alpha subunit (approx. 80 kDa) expressed e.g. by neutrophils, eosinophils, monocytes and macrophages.
Formulation	Tris buffered saline (TBS), pH~8.0 State: Purified State: Liquid purified Ig fraction (> 95% by SDS-PAGE) Preservative: 15 mM Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	colony stimulating factor 2 receptor alpha subunit
Database Link	Entrez Gene 1438 Human UniProt ID P15509
Background	CD116 (GM-CSF R alpha) is the low affinity receptor for granulocyte-macrophage colony-stimulating factor (GM-CSF). CD116 heterodimerizes with CD131, the common beta chain subunit shared with IL-3 and IL5 receptors, to form the high affinity GM-CSF receptor. CD116 is expressed by myeloid cells including macrophages, neutrophils, eosinophils, dendritic cells, and their precursors, as well as on endothelial cells. It is being used as a specific marker of myeloid leukemias.
Synonyms	GM-CSF-R-alpha, GMR, CSF2R, CSF2RY, GMCSF Receptor alpha, GM-CSF Receptor alpha
Reference Data

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