EVI2B Mouse Monoclonal Antibody [Clone ID: MEM-216]

Specifications

Product Data
Clone Name	MEM-216
Applications	FC, IP
Recommend Dilution	Flow cytometry. Positive control: Raji, Daudi, HL-60 cells, peripheral blood lymphcocytes (strongly positive on CD19+ cells) Negative control: Jurkat, U-937 cells. Immunoprecipitation.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Raji cells
Specificity	This antibody detects CD361.
Formulation	Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein A affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	ecotropic viral integration site 2B
Database Link	Entrez Gene 2124 Human UniProt ID P34910
Background	CD361, also known as EVI2B (Ecotropic Viral Integration site 2B) or EVDB, is a poorly characterized type I transmembrane protein, expressed from one of three genes embedded in intron 27b of the neurofibromatosis type 1 (NF1) gene. The DNA strand that is transcribed to produce CD361 is the complementary one to the strand encoding NF1. Murine homolog to human CD361 is associated with ecotropic viral insertions, which have been implicated in the expression of murine myeloid leukemias. CD361 has been also reported to be involved in melanocyte and keratinocyte differentiation. However, it is expressed mainly in peripheral blood and bone marrow.
Synonyms	EVDB
Reference Data

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