Lin28 (LIN28A) Mouse Monoclonal Antibody [Clone ID: 55CT58.12.1]

Specifications

Product Data
Clone Name	55CT58.12.1
Applications	IHC, WB
Recommend Dilution	ELISA: 1/10000. Western blotting: 1/200-1/2000. Immunohistochemistry: 1/50-1/200.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	LIN28A recombinant protein is used to produce this monoclonal antibody.
Specificity	This antibody is specific to LIN28A.
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	lin-28 homolog A
Database Link	Entrez Gene 79727 Human UniProt ID Q9H9Z2
Background	LIN28A acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in stabilizing the mRNAs. Binds IGF2 mRNA, MYOD1 mRNA, ARBP/36B4 ribosomal protein mRNA and its own mRNA. It is essential for skeletal muscle differentiation through the translational up-regulation of IGF2 expression.
Synonyms	LIN-28, LIN28A, CSDD1, ZCCHC1
Reference Data

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.