Fxyd1 Mouse Monoclonal Antibody [Clone ID: 41AT858.235]

Specifications

Product Data
Clone Name	41AT858.235
Applications	WB
Recommend Dilution	ELISA: 1:1,000 Western blotting: 1/100-1/500.
Reactivity	Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	This monoclonal antibody is generated from mice immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Ser68 of mouse PLM.
Specificity	This antibody is specific to PLM at Ser68.
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	FXYD domain-containing ion transport regulator 1
Database Link	Entrez Gene 56188 Mouse UniProt ID Q9Z239
Background	PLM (FXYD1)is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. PLM may be phosphorylated by several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity.
Synonyms	FXYD1, PLM
Reference Data

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