Transglutaminase 3 (TGM3) Mouse Monoclonal Antibody [Clone ID: B5D]

Specifications

Product Data
Clone Name	B5D
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western Blot: 1/200-1/1000. Immunohistochemistry: 1/100-1/500.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Human Transglutaminase-3
Specificity	Reacts with Human TGase-3 from Human epidermal cells and recombinant Tgase-3 (rh-TG-3). This antibody recognizes both full length (77 kDa) and proteolysed forms (30 kDa).
Formulation	0.1M Tris, 0.1M Glycine and 2% Sucrose State: Purified State: Lyophilized purified antibody Preservative: None
Reconstitution Method	Restore in distilled water.
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Predicted Protein Size	77 kDa
Gene Name	transglutaminase 3
Database Link	Entrez Gene 7053 Human UniProt ID Q08188
Background	Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis. The encoded protein is involved the later stages of cell envelope formation in the epidermis and hair follicle.
Synonyms	TGase, TGE
Reference Data

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