HMB45 Mouse Monoclonal Antibody [Clone ID: HMB45]

Specifications

Product Data
Clone Name	HMB45
Applications	IHC
Recommend Dilution	Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Sections: 1/100 Pretreatment of deperaffinized tissue with heat-induced epitope retrieval is recommended. Use Polymer anti Mouse/Rabbit IgG as a detection system. Positive Control: Melanoma.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Extract of pigmented melanoma metastases from lymph nodes.
Specificity	By Immunohistochemistry, HMB-45 specifically recognizes a protein in melanocytes and melanomas. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Cellular Localization: Cytoplasmic.
Formulation	State: Supernatant State: Tissue Culture Supernatant with 0.2% BSA and 15mM Sodium Azide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Background	Malignant melanoma is a malignant neoplasm of melanocytes, arising de novo or from a pre existing benign nevus, which occurs most often in the skin but also may involve other sites.
Synonyms	HMB45 Melanoma Marker
Reference Data

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