elF2 alpha (EIF2S1) Mouse Monoclonal Antibody [Clone ID: AT5E10]

Specifications

Product Data
Clone Name	AT5E10
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western blot (1:1,000). Immunohistochemistry on Paraffin Sections (10 µg/ml).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human EIF2S1 (1-315aa) purified from E. coli
Specificity	The antibody recognizes human EIF2S1. Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	eukaryotic translation initiation factor 2 subunit alpha
Database Link	Entrez Gene 1965 Human UniProt ID P05198
Background	Eukaryotic translation initiation factor 2, subunit 1 alpha (EIF2S1) is plays a central role in initiating translation, and provides for a rate-limiting step in protein synthesis. The phosphorylation of alpha-subunit of EIF2S1 effectively prevents formation of the EIF2S1/GTP/Met-tRNAi complex and inhibits global protein synthesis.
Synonyms	EIF2-A, eIF-2A, eIF-2-alpha, eIF-2alpha, eIF2 alpha
Reference Data

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