PSMA (FOLH1) Mouse Monoclonal Antibody [Clone ID: 7F3]

CAT#: AM09257PU-N

PSMA (FOLH1) mouse monoclonal antibody, clone 7F3, Aff - Purified



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CNY 6,120.00


货期*
4周

规格
    • 500 ug

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Specifications

Product Data
Clone Name 7F3
Applications ELISA
Recommend Dilution ELISA.
In Indirect ELISA this antibody is reactive to PMSA expressing LNCap cells coated ELISA plate.
Reactivity Human
Host Mouse
Clonality Monoclonal
Immunogen Crude membrane protein extraction from PSMA expression LNCap cells, and a PSMA derived peptide (ESKVDPSKA) coupled with KLH.
Specificity This antibody is reactive to PSMA expression LNCap cells and the KLH conjugated PSMA peptide.
Little or no cross-reactivity to KLH and BSA.
Formulation 0.01M PBS, pH 7.0
State: Aff - Purified
State: Lyophilized purified IgG fraction
Stabilizer: None
Preservative: None
Reconstitution Method Restore with Double distillated water to adjust the final concentration to 1.0 mg/ml.
Concentration 1.0 mg/ml (after reconstitution)
Purification Affinity Chromatography on Protein G
Conjugation Unconjugated
Storage Condition Store lyophilized at 2-8°C for 6 months or at -20°C long term.
After reconstitution store the antibody undiluted at 2-8°C for one month
or (in aliquots) at -20°C long term.
Avoid repeated freezing and thawing.
Gene Name folate hydrolase (prostate-specific membrane antigen) 1
Background Prostate Specific Membrane Antigen (PMSA, FOLH1) is a type II transmembrane glycoprotein belonging to the M28 peptidase family. Three functionally distinct proteins are encoded, including folylpoly-gamma-glutamate carboxypeptidase in the intestine, N-acetylated alpha-linked acidic dipeptidase 1 in the brain, and prostate-specific membrane antigen in the prostate. A mutation in the intestinal form may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. The form expressed in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. The prostate form is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants.
Synonyms Glutamate carboxypeptidase 2, Folate hydrolase 1, Prostate-specific membrane antigen, FOLH, NAALAD1, PSM, GCP2, NAALAdase
Reference Data
Protein Families Druggable Genome, Protease, Transmembrane
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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