CEACAM5 Mouse Monoclonal Antibody [Clone ID: CEA-Y2]

Specifications

Product Data
Clone Name	CEA-Y2
Applications	ELISA, WB
Recommend Dilution	ELISA: The antibody can be used in sandwich ELISA for detection of CEA in combination with matched capture antibody Clone CEA-Y1 (Cat.-No AM09247PU-N). Western Blot: 25 ng/lane of antigen can be detected when the antibody was used at 100 ng/ml.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human Carcinoembryonic Antigen (CEA).
Specificity	Recognizes Carcinoembryonic Antigen CEA. Cross-reactivity with other Human protein was not found.
Formulation	0.01M PBS, pH 7.0 State: Aff - Purified State: Lyophilized purified IgG fraction
Reconstitution Method	Restore with Double distilled water to adjust the final concentration to 1.0 mg/ml.
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Upon receipt, store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	carcinoembryonic antigen related cell adhesion molecule 5
Database Link	Entrez Gene 1048 Human UniProt ID P06731
Background	Carcinoembryonic Antigen (CEA) is a 180-200 KD glycoprotein expressed at high level in the epithelial cells of the embryonic colon. The expression is stopped after birth. CEA serum content is low in normal population and only slightly elevated in heavy smokers. Increased serum CEA level was found to be associated with colorectal carcinoma, gastric carcinoma, pancreatic carcinoma, lung carcinoma, and breast carcinoma. However elevated CEA level does not necessarily indicate neoplastic conditions. CEA level is useful for monitoring tumour recurrence after surgical resection of carcinoma.
Synonyms	CEA, Carcinoembryonic antigen
Reference Data

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