alpha 1 Fetoprotein (AFP) Mouse Monoclonal Antibody [Clone ID: AFP-Y2]

Specifications

Product Data
Clone Name	AFP-Y2
Applications	ELISA
Recommend Dilution	ELISA: In combination with capture antibody Clone AFP-Y1 (Cat.-No AM09237PU-N), this HRP conjugated antibody can be used as tracer antibody in sandwich ELISA assay for Human AFP detection.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human AFP, which was isolated from amniotic fluid and purified by affinity chromatography.
Specificity	This AFP-Y2 antibody react with AFP. No detectable cross reaction with Human normal serum proteins.
Formulation	0.01M PBS, pH 7.2 with 50% Glycerol Label: HRP State: Liquid purified IgG fraction
Purification	Affinity Chromatography on Protein G
Conjugation	HRP
Storage Condition	Upon receipt, store (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	alpha fetoprotein
Database Link	Entrez Gene 174 Human UniProt ID P02771
Background	Alpha-fetoprotein is a major plasma protein produced by the yolk sac and the liver during fetal life. alpha Fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha Fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha Fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. alpha Fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha Fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Synonyms	Alpha-1-fetoprotein, Alpha-fetoglobulin, HPAFP
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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