CRABP1 Mouse Monoclonal Antibody [Clone ID: AT1A1]

Specifications

Product Data
Clone Name	AT1A1
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western blot: 1/500-1/1,000. Immunohistochemistry on Paraffin Sections: 5 µg/ml.
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Human CRABP1 (1-137 aa) purified from E. coli
Specificity	The antibody recognizes Human and Mouse CRABP1. Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	cellular retinoic acid binding protein 1
Database Link	Entrez Gene 12903 MouseEntrez Gene 1381 Human UniProt ID P29762
Background	CRABP1 (cellular retinoic acid-binding protein 1) is a member of specific carrier proteins for members of the vitamin A family. CRABP1 is assumed to play an important role in retinoic acid-mediated differentiation and proliferation processes. CRABP1 is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid. It is constitutively expressed and is believed to have different functions in the cell than the related CRABP2. Interestingly, Sytenol A bakuchiol has very specific receptor specificity over retinol and has no effect on the RAR-beta and RAR-gamma receptors and down-regulates CRABP1.
Synonyms	CRABP-I, RBP5
Reference Data

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