LITAF Mouse Monoclonal Antibody [Clone ID: AT5C10]

Specifications

Product Data
Clone Name	AT5C10
Applications	ELISA, FC, WB
Recommend Dilution	ELISA. Western blot (1/2000-1/3000). Flow CYtometry.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human LITAF (1-161 aa) purified from E. coli
Specificity	The antibody recognizes Human LITAF. Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	lipopolysaccharide induced TNF factor
Database Link	Entrez Gene 9516 Human UniProt ID Q99732
Background	Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LITAF) mediates the expression of inflammatory cytokines such as TNF-alpha in Lipopolysaccharide-induced processes. LITAF binds to STAT6B, a member of the STAT6 family forming a complex on the TNF-alpha promoter that modulates TNF activity. High levels of expression of LITAF mRNA have been observed predominantly in the placenta, peripheral blood leukocytes, lymph nodes and spleen.
Synonyms	LITAF, PIG7, SIMPLE, LPS-induced TNF-alpha factor, p53-induced gene 7 protein
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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