DACT3 Mouse Monoclonal Antibody [Clone ID: 2A5]

Specifications

Product Data
Clone Name	2A5
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western blot (1:250 - 500) . Immunohistochemistry on Paraffin embedded tissues (1:50).
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human DACT3 (aa 89-202) purified from E. coli
Specificity	The antibody recognizes human and mouse DACT3. Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	dishevelled binding antagonist of beta catenin 3
Database Link	Entrez Gene 629378 MouseEntrez Gene 147906 Human UniProt ID Q96B18
Background	DACT3, a member of the DACT (Dpr/Frodo) gene family, plays an important role in a negative regulator of Wnt/-catenin signaling. Unlike other Wnt signaling inhibitors that are silenced by DNA methylation, DACT3 repression is associated with bivalent histone modifications.
Synonyms	dapper homolog 3, DAPPER3, RRR1
Reference Data

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