EPM2A Mouse Monoclonal Antibody [Clone ID: k2A3]

Specifications

Product Data
Clone Name	k2A3
Applications	ELISA, FC, WB
Recommend Dilution	ELISA. Western blot (1/1,000-1/2,000). Flow Cytometry.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human EPM2A (aa 243-331) purified from E. coli
Specificity	The antibody recognizes EPM2A.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein-G affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
Database Link	Entrez Gene 7957 Human UniProt ID O95278
Background	Epilepsy, progressive myoclonus type 2A (EPM2A), also known as laforin, is a dual-specificity phosphatase that associates with polyribosomes. The protein may be involved in the control of glycogen metabolism, particularly in monitoring for and preventing the formation of poorly branched glycogen molecules. Defects in EPM2A are a cause of progressive myoclonic epilepsy type 2(EPM2), also known as Lafora disease. EPM2 is an autosomal recessive and severe form of adolescent-onset progressive epilepsy.
Synonyms	EPM2A, Laforin, EC=3.1.3.48, EC=3.1.3.16, Lafora PTPase, LAFPTPase
Reference Data

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