PSMA (FOLH1) Mouse Monoclonal Antibody [Clone ID: k1H7]

Specifications

Product Data
Clone Name	k1H7
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western blot: 1/1,000-1/3,000 (recommended starting dilution is 1/2,000). Immunohistochemistry on Paraffin Sections: 5 µg/ml after heat induced antigen retrieval in pH 6.0 citrate buffer.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant Human PSMA (117-351 aa) purified from E. coli
Specificity	The antibody recognizes Human PSMA. Other species not tested.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	folate hydrolase (prostate-specific membrane antigen) 1
Database Link	Entrez Gene 2346 Human UniProt ID Q04609
Background	Prostate-specific membrane antigen (PSMA) is a 100-120 kDa type II transmembrane glycoprotein that is a glutamate-preferring carboxy-peptidase. Three functionally distinct proteins are encoded, including folylpoly-gamma-glutamate carboxypeptidase in the intestine, N-acetylated alpha-linked acidic dipeptidase 1 in the brain, and prostate-specific membrane antigen in the prostate. PSMA is highly expressed in prostate secretory-acinar epithelium, in some benign extraprostatic epithelial cells from breast, duodenum, and kidney tissues, and in prostate cancer.
Synonyms	Glutamate carboxypeptidase 2, Folate hydrolase 1, Prostate-specific membrane antigen, FOLH, NAALAD1, PSM, GCP2, NAALAdase
Reference Data

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