Phosphoserine phosphatase (PSPH) Mouse Monoclonal Antibody [Clone ID: 3G12]

Specifications

Product Data
Clone Name	3G12
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western blot (1/1,000-1/2,000) Recommended Starting Dilution: 1/1,000. Immunohistochemistry on Paraffin Sections (10 µg/ml).
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant human PSP (1-225 aa) purified from E. coli
Specificity	The antibody recognizes Phosphoserine Phosphatase.
Formulation	PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein-A affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	phosphoserine phosphatase
Database Link	Entrez Gene 5723 Human UniProt ID P78330
Background	Human phosphoserine phosphatase (HPSP), specific for D- and L- phosphoserine, has been identified in all human tissues. HPSP is a Mg(2+)-dependent phosphoserine phosphatase. The three dimensional structure of HPSP reveals the structural and functional role of the divalent cation in the active site of phosphatases. In particular, the complex structures reveal that the open-closed environmental change of the active site, generated by local rearrangement of the alpha-helical bundle domain, is important for the substrate recognition and hydrolysis.
Synonyms	PSPH, PSPase, PSP, EC=3.1.3.3, O-phosphoserine phosphohydrolase, L-3-phosphoserine phosphatase
Reference Data

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