CD16 (FCGR3A) Mouse Monoclonal Antibody [Clone ID: GRM1]
CAT#: AM08159FC-N
CD16 (FCGR3A) mouse monoclonal antibody, clone GRM1, FITC
Conjugation: Unconjugated Biotin PE
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CNY 4,136.00
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Specifications
Product Data | |
Clone Name | GRM1 |
Applications | FC |
Recommend Dilution | Flow Cytometry: 10 µL/10e6 cells. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Specificity | This antibody recognizes CD16/FcgammaRIII. |
Formulation | PBS containing 0.09% Sodium Azide as preservative. Label: FITC State: Liquid purified Ig fraction. Label: Fluorescein Isothiocyanate Isomer 1 |
Conjugation | FITC |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or in (aliquots) at -20°C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing. |
Gene Name | Fc fragment of IgG receptor IIIa |
Database Link | |
Background | CD16 (FcgammaRIII) serves as a low affinity IgG receptor. Human CD16 is expressed in two forms CD16a and CD16b. CD16a is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. CD16b is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype. CD16 is involved in NK activation and signal transduction. (Ref.1-5) |
Synonyms | FCGR3A, CD16A, FCG3, FCGR3, IGFR3, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcR-10, IgG Fc receptor III-2 |
Reference Data | |
Protein Families | ES Cell Differentiation/IPS, Secreted Protein, Transmembrane |
Protein Pathways | Fc gamma R-mediated phagocytosis, Natural killer cell mediated cytotoxicity, Systemic lupus erythematosus |
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