CD20 (MS4A1) Mouse Monoclonal Antibody [Clone ID: B-Ly1]

Specifications

Product Data
Clone Name	B-Ly1
Applications	FC, FN, IP
Recommend Dilution	Flow Cytometry: < / = 1 µg/10e6 cells. Immunoprecipitation. In vitro activation of B cells.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Specificity	This antibody recognizes CD20.
Formulation	Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	membrane spanning 4-domains A1
Database Link	Entrez Gene 931 Human UniProt ID P11836
Background	CD20 is a non glycosylated protein with a molecular weight of 35 or 37 kDa depending on the degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca++ channel subunit. (Ref-1-4)
Synonyms	MS4A1, Leu-16, Bp35, B-cell marker
Reference Data

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